Tumor Heterogeneity, Plasticity and Therapy

Within a tumor, many cancer cells differ from each at the (epi-)genomic, transcriptional and proteomic level, as well as phenotypically and functionally. Tumor heterogeneity represents a major hurdle for therapy, which may only target a subset of tumor cells. In addition, cancer cell plasticity permits rapidly adaption to therapeutics and development of tolerance and resistance, presenting additional challenges for both targeted and immunotherapies.

During this conference a range of world leaders from academia and industry will discuss the latest developments in basic research, translational and clinical research and therapeutic avenues, in the following sessions:

• Plasticity in initiation, progression and metastasis

• Heterogeneity and reprogramming of the tumor immune- and microenvironment

• Adaptation and resistance to targeted therapies

• Adaptation and resistance to immunotherapies

Programme, abstracts & travel grants

Please visit the conference website for more information.