Principal Scientist Biophysics/Formulation (Location: Ghent)



Technologiepark 73A Zwijnaarde (Gent) Belgium

Function type

Principle Scientist


Aelin Therapeutics is a biopharmaceutical company pioneering peptide-based novel drug modalities to create powerful first-in-class antibiotics and agents against high-value undruggable human targets in oncology. The technology, branded Pept-ins™, harnesses the power of protein aggregation to induce specific functional knockdown of a target protein. The Pept-in™ technology allows for the rational design of novel peptide-based therapeutics and differentiates itself from other therapeutic modalities through its unique mode of action, its designability and broad target space.

Aelin Tx is looking for a Principal Scientist Biophysics /Formulation/Analytics who will be based in our brand new facilities at the Tech Lane park in Ghent.

As Principal Scientist Biophysics/Formulation/Analytics, your main focus is to find solutions to control the self aggregation tendency of peptides in order to allow the further successful development of the company's lead compounds. You will manage the biophysics and analytics teams, making it imperative that you drive projects from a scientific point of view, while managing all the parties involved and maintaining timelines and generating results.

Do you recognize yourself in this profile?

  • You have a PhD (or MSc. backed by working experience) in biophysics, chemistry or a related discipline

  • You have 15 years of industrial experience, of which 8 years of biophysics/analytics experience

  • You have strong leadership skills, and will oversee both the biophysics and analytics teams

  • You bring expertise in development, characterization, chemical analysis and bioanalysis of candidate drugs such as peptides, vaccines, proteins and/or antibodies towards clinical development

  • You are skilled in a broad set of techniques for biophysical characterization (e.g. DLS, SLS, MALS, PFI, BMI) and separation (e.g. SEC, AF4)

  • You enjoy liaising and monitoring the work of CRO/CDMO/vendors

  • Fluent in English, both verbal and written

The company offers an entrepreneurial and stimulating working environment in an ambitious and dynamic biotech company, working with top entrepreneurs and innovators in the biotech industry.

You will have freedom to shape your work and shape your job. Your input is highly appreciated.

Next to a competitive salary and benefits package, we offer you the chance to grow and be a part of the Aelin team driven by innovation and science to develop new therapies.

Do you have the right qualifications, a bright mind, sharp instincts, collaborative spirit, and innovative vision and are you interested in joining our entrepreneurial team? Then forward a short motivation and CV to

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