Research Associate Drug Product Development

General job description

The Research Associate Drug Product Development is responsible for the execution of formulation development activities related to drug delivery systems used for delivery of nucleic acids to different organs and cells, under the supervision of a Senior Scientist Drug Product Development.

The Research Associate role is a hands-on position focused on experimental laboratory work and techniques for stability study, manufacturing feasibility assessment and scale-up of RNA formulations.

The candidate will be part of the Drug Product Development team and the role is a permanent position. This position reports to Senior Scientist Drug Substance and Drug Product Development and will be based in Gent as described above.

Responsibilities and Duties

The Research Associate Drug Product Development’s duties shall include, but not be limited to:

• Preparation of LNPs using micro-fluidic mixing, T-mixing and impingement jets mixing

• Quenching and ethanol removal by dialysis and TFF, sterile filtration

• Lyophilization of mRNA/LNPs

• Analytical techniques including size and PDI by zetasizer, pH, osmolality, encapsulation efficiency, mRNA content, integrity, water content

• Assist in development of new techniques and assays

• Participate in lab supply ordering, inventory management, maintenance of equipment and lab areas

• Data processing, data analysis and good documentation practices using electronic lab notebook, protocol- and report writing

Job requirements

Education:

Bachelor's in biotechnology/laboratory science, biomedical sciences or similar

Experience:

• Minimum of 1 year of relevant experience in academic or biotech industry In a similar function. Recently qualified Bachelors may be considered

• Broad technical expertise and mastering of several laboratory techniques

• Working knowledge of good laboratory practices and lab quality assurance is a plus

 Other Qualifications, Skills and Abilities:

• Detail-oriented and accurate in following instructions, record keeping and completion of reports

• Able to perform experimental troubleshooting and propose technical solutions.

• Scientific integrity

• Ability to work collaboratively and communicate effectively with internal teams.

• Fluent in English;

• Well-organized, well-structured, hands-on, result-focused;

• Able to work under stringent timelines

• Enthusiastic, proactive, flexible and able to multitask;

• Understanding of MS Office (Excel, Word, PowerPoint, Outlook).

Our offer

• An exciting job in a fascinating and entrepreneurial environment with room for personal development and initiative

• Employment contract of unlimited duration with a competitive salary package with a lot of extra benefits (reimbursement of commuting cost, meal & eco vouchers, group & hospitalisation insurance, bonus & warrants)

• Work within a dynamic and innovative group with great colleagues