Senior Associate Scientist CMC Analytics



Technologiepark-Zwijnaarde 21, Gent, Belgium

Function type

Senior Associate Scientist


Senior Associate Scientist CMC Analytics 

About the Opportunity 

As a Senior Associate Scientist in the CMC team, you will be mainly working in the lab. You will be part of the team responsible for the in-depth analysis of the quality and stability of lead Nanobodies┬« during pre-clinical and clinical development. It is a dynamic team, involved in various aspects of nanobody drug development working with a range of analytical methods. 

About Ablynx and the CMC Analytical team 

Ablynx is a biopharmaceutical company dedicated to creating new antibody-based medicines called Nanobodies which will make a real difference to society. Ablynx has currently over 400 people working on the development of Nanobodies for the treatment of a wide range of diseases, including inflammation, hematology, respiratory disease, immuno-oncology and oncology. 

The Analytics group of the CMC Pharmaceutical Development & Technology Department at Ablynx is a dynamic, international team consisting of ~37 people with different levels of experience. You will have the opportunity and the challenge to work with many different techniques using state-of-the-art equipment. 

The CMC analytical team is responsible for non-GMP R&D activities to support Nanobody discovery, developability and (pre)-clinical development activities such as: 

  • Formulation studies 

  • Method development and qualification 

  • Release and stability studies 

  • In-process monitoring and control 

  • Characterization of the product-related variants 

  • In-use stability and compatibility 

About growing with us 

A multitude of assays are being used in the team including standard techniques such as Reversed Phase, Size Exclusion and other (U)HPLC chromatography, UV- and fluorescence spectroscopy, capillary electrophoresis, Dynamic Light Scattering (DLS), Micro-Flow Imaging (MFI), light obscuration, osmolality and viscosity measurements, endotoxin testing, Host Cell Proteins assay (...). 

In this role, you will be involved in routine analysis, including: 

  • Support other departments by performing requested analytical tests 

  • Controlling the quality and consistency of Nanobody productions and thereby assisting in the development of a large-scale manufacturing process for a specific lead Nanobody 

  • Depending on the ongoing projects, you can also be involved in: 

    • Stability studies 

    • Performing physico-chemical characterization of Nanobodies, identification of product variants and investigation of degradation pathways

 About you 

 Qualifications/Education & work experience 

  • Bachelor degree or master degree in life sciences. or equivalent, with at least 2 to 5 years of experience in laboratory work  

  • Hands-on mentality and comfortable with controlling high tech instrumentation 

  • Hands-on experience and able to develop in-depth technological know-how of some of the analytical methods listed above  

  • Experience in physico-chemical analysis of proteins is an asset  


  • Able to work independently and in team, enthusiastic and self-motivated 

  • Ability and desire to work in a fast-paced, dynamic environment 

  • Good sense for initiative, quality, accuracy and detail 

  • Team player 

  • Ability to plan and perform experiments and to prepare concise reports of the results in English 

  • Knowledge of English  

Your CV should be in English, and include a paragraph specifying your technical expertise. 

As a standard, a temporary contract (12 months) will be offered to junior candidates. This is with the intention of converting to a permanent contract after a year. 

Inspire your Journey, what Sanofi can offer you 

  • An international work environment, in which you can develop your talent and realize ideas and innovations within a competent team 

  • An individual and well-structured introduction and training when you onboard 

  • You can create your own career path within Sanofi. Your professional and personal development will be supported purposefully 

  • As a globally successful and constantly growing company, Sanofi provides international career paths as well 

This is our Sanofi, Discover yours. 

We are proud to have been awarded Global Top Employer 2021.


At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

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