GSK R&D, Upstream Scientist
GSK R&D, Upstream Scientist
Rue de l'institut 89, Rixensart, Belgium
Are you energized by a challenging role in biology, where scientific demand is driving team growth? If so, this Scientist Upstream role would be a great opportunity to consider.
As a Scientist specialized in the upstream/fermentation field, you will join a team of experts focusing on Drug Substance process development for new vaccine candidates from Phase I up to commercial launch. You will also be involved in Life Cycle activities for process improvements in the commercial vaccine portfolio.
You will be expected to lead autonomously the USP part (bacterial fermentation) of several drug substance development projects in parallel, driving implementation of latest industry trends and state-of-the-art technologies into current manufacturing processes, identifying and promoting opportunities for improvements aiming for scalable, high efficiency, robust, and cost-effective manufacturing processes with reduced-footprint
You will be expected to have strong project management skills and perform timeline and resource planning estimations, design development strategies, plan experimental protocols, lead horizontally a team of technicians and operators to execute them, having a strong presence in the lab to ensure best practices, compliance with documentation practices and EHS standards.
You will be expected to follow the Quality by Design approach to process development, leading multi-disciplinary Technical Risk Assessments and ensuring to meet all documentation deliverables required at each of the project stage gates
You will be expected to support the Development Unit Head in bringing the team (both in your own development unit as well as in the others across the department) to the next level in technical knowledge and best practices, proactively promoting initiatives
You will ensure a strong interface and knowledge sharing with, Manufacturing Science and Technology, manufacturing strategy, site management, Process Science, and engineering departments for building-related activities such as revamping, scaling-up or tech transfer to new facilities.
You will work very closely with the Scale-up team from the development stages to ensure a smooth transition throughout the scales required at the different project phases.
You will closely collaborate with the In-Process Analytical organization to develop IPA strategy and implement IPA testings as fit for upstream processes.
You will build strong relationships and a collaborative network with the DS organizations in Italy and the US aimed at increasing sharing and learning, better decision making, stimulating people development and pushing top science & technology throughout the network.
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