Junior Project Manager - Translational Science

2 Bridge company

2 Bridge is a Belgian-based company that provides advice and support on all key disciplines of healthcare product development (discovery, pre-clinical, clinical and product development, registration and life-cycle management). We work globally with startups, biotech, pharma, and investors.

2 Bridge typically operates via flexible and cross-functional teams, aligned to the project need. Our broad and multidisciplinary expertise allows us to address the most complex and challenging tasks during development. For more information, please visit: www.2Bridge.be.

Job description

We are looking for a junior Project Manager Translational Science with a keen interest to learn about managing projects for a clinical study.

In a significant number of projects that 2 Bridge supports, a transition is made from research to development. For these projects, we want to expand our team with a Translational Sciences R&D Manager with a keen interest in supporting drug development and managing projects.

The Translational Sciences R&D Manager will be involved in design and execution of drug development plans and due diligences assessments, under the guidance of a senior professional.

You will support a wide variety of activities centered around strategic positioning, planning and management of preclinical activities as part of a drug development plan in preparation of FIH and POC studies; often at contract research organization (CROs), in various therapeutic areas are modalities, having thus the opportunity to broaden expertise quickly.

As part of 2 Bridge multidisciplinary teams, you will interact with 2 Bridge experts from all areas of drug development, spanning from CM&C to medical and clinical operations. Close collaboration with internal or external experts, key opinion leaders and sponsors’ own teams is a key aspect of this job. 

Key activities of a Translational Sciences (Senior) R&D Manager are:

• Substantiation of scientific research by datamining, including but not limited to literature research, data analysis, gap-analysis, epidemiologic data evaluation, …;

• Manage discovery and preclinical research projects;

• Direct verbal and written communications with clients and their designees including other vendors and investigators, researchers and authors;

• Manage project deliverables within timelines and within the approved budget;

• Ensure of compliance with applicable regulations and guidelines throughout activities;

• Develop / improve of procedural documents and processes.

• Support creation and implementation of DMPK, preclinical safety and pharmacology aspects (including biomarkers) of a development strategy towards IND/CTA applications.

• Execute agreed development strategy under support of a senior leader.

• Support identification, selection, and studies execution at preclinical service providers.

• Support due diligence assessments on compounds or platforms, integrating preclinical learnings from shared data, literature, and databases, in broader multidisciplinary analysis resulting in SWOT analysis and recommendations.

• Within DMPK, preclinical safety and pharmacology area: prepare documentation for discussion with either scientific advisory board, investors, or regulatory agencies interaction.

• Support generation of early clinical development plans, providing inputs from preclinical safety and pharmacology and supporting translational biomarker definition.

What we offer

Be part of a multidisciplinary team that values versatility, adaptability, and effective cross-functional collaboration, in the spirit of our values: ‘we care, we adapt, we drive to excel’. By being exposed to a multitude of projects and functions, you will quickly gain a broader view of drug development, thereby enhancing your professional growth.

You will work in a non-hierarchical environment that highly values teamwork and where you will have the freedom to shape your role. We believe in fostering a culture of learning and continuous feedback, where everyone feels supported and empowered to succeed.

We build a safe work environment where people feel comfortable speaking up, taking accountability, and balancing their personal boundaries with business expectations. Our team collaborates and supports each other, creating a dynamic and inclusive workplace where you can thrive.

Qualifications/Desired profile

• PhD in Bio-medical sciences, Pharmacy, or equivalent.

• Ideally 3 years of prior drug development experience within startup/ biotech/ relevant pharma industry setting (toxicology, DMPK, translational sciences, discovery); although industry-starters with the right mind-set will also be considered.

• Solid background in at least a therapeutic area of interest for 2 Bridge: oncology, neurology, immunology.

• Experience in DMPK or toxicology is a plus.

• Enthusiasm with a keen interest to learn and expand knowledge towards broader picture of drug development, not limited to but including CMC, clinical development, and entrepreneurship.

• Interested in working in a multidisciplinary team (often including external people), but with the ability to work independently.

• Analytical, pro-active, flexible and with an eye for detail.

• Good communication skills: oral, written and presenting.

• Fluency in English (especially in writing) is a must.

How to apply

CV, motivation letter where you:

• Introduce yourself

• Explain why you are interested in the job

• Outline why you think you are the right candidate

Interested? Please send your motivation letter and CV to HR@2bridge.be.