Monday June 20th 2022

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Mithra (Euronext Brussels: MITRA), a company dedicated to Women’s Health, today announces that Mr. François Fornieri resigned from his non-executive director mandate of the Company. Mr. Fornieri ’s decision, founder and major shareholder of the Company, is based on personal reasons.

At the end of this transitional year within the new Board of Directors in place since May 2021, I have decided, not without some emotion, to resign from my role as director. As a major shareholder, I restated my full confidence in the management team in place during the latest Shareholder’s Meeting, as well as in the directors, all of whom were appointed by large majorities. Over the past year, I closely worked with the CEO and the Directors in order to transfer all my knowledge of this company which I managed for 22 years. I strongly believe that they have all the necessary expertise to lead the Company in its next strategic phases, in particular the conclusion of a commercial partnership agreement for Donesta® in the coming months. It is now time for me to dedicate my energy and expertise as an entrepreneur to other professional projects. As Mithra’s founder and major shareholder, I will obviously continue to monitor closely its achievements and promising projects. Thanks to the strong intellectual property we have built around estetrol, I am confident that new developments will bring Mithra at the place it deserves in the biotech world.